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The extension also happens to make the construct convenient to express in a bacterial host, which is part of why this particular variant became the standard reagent for serum-free and low-serum media development rather than remaining a curiosity
However, each bile acid can trigger distinct responses in the brain and its various cell types
The five-on, two-off pattern gives the pituitary regular off-days rather than steady, uninterrupted signaling
Some proteins have layered stacks of -sheets, which impart structural integrity and may open to form a cavity (a beta barrel)
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