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The Neelakantan 2018 study reported that 5-Amino-1MQ administration to diet-induced obese mice produced reductions in adipose-tissue NNMT enzymatic activity, with concurrent reductions in fat mass and improvements in glucose tolerance [1]
The difference is substantial but not insurmountable
49 Hoffer, L
Link below outlines UK treatment patterns for people with B12 deficiency aged 16 onwards cks.nice.org.uk/topics/anae
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