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The right protocol, the right product, and the right team make all the difference
In terms of statistical analysis, various efficacy analyses were performed in all participants that went through the randomization process while safety analysis were used to assess all participants that underwent randomization and were also exposed to one experimental treatment dosage
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A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007
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