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Disclaimer: This information is for educational purposes only and does not constitute medical advice
R Met/Met individuals have higher synaptic dopamine and norepinephrine (because COMT clears them more slowly), which improves prefrontal cortex function and working memory but increases susceptibility to stress-related anxiety, pain sensitivity, and catechol estrogen accumulation
Our Edmonton athletes often preload with IVs before big events and swear by the recovery boost afterward
The standard research protocol is 300 mcg per day, subcutaneous, administered in a fasted state, typically in the morning before food or exercise
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