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234 TGF- signaling pathway The transforming growth factor- (TGF-) superfamily, including TGF-1/2/3, bone morphogenetic proteins (BMPs), activins, and nodal, exerts pleiotropic effects on cancer biology, with context-dependent roles as both a tumor suppressor and promoter
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, 20 , 3672, doi: Bansal, A., and Simon, M
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