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Clinical Evidence: REDEFINE Program# REDEFINE 1 (Without Type 2 Diabetes)# 3,417 adults randomized to CagriSema (n=2,108), semaglutide alone (n=302), cagrilintide alone (n=302), or placebo (n=705) for 68 weeks
[Abstract]2025 Jun 11
Mood swings Irritability or emotional sensitivity during the inflammatory window
Combining tirzepatide with vitamin B12, a common additive in compounded versions of the drug, yields an impurity that could alter the drugs toxicity profile and pose safety risks to patients, the company said in an open letter
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