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The six IGFBPs serve as carrier proteins that bind approximately 98% of all circulating native IGF-1, with binding affinity equal to or greater than that of the IGF-1 receptor itself meaning the vast majority of native IGF-1 is sequestered before reaching its receptor

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Every batch independently HPLC-verified to 99% purity with a batch-specific Certificate of Analysis

This trend toward earlier-phase trial disclosures could also be seen in updates to the US Food and Drug Administration (FDA) Good Clinical Practice (GCP) guidelines and EU CTR rules