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GLP-1 medications require consistent adherence, may require lifestyle modifications, and come with a titration period during which side effects are common

Thus, whether TMAO is an atherogenic factor responsible for the development and progression of cardiovascular disease, or simply a marker of an underlined pathology, remains unclear [85]

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Moreover, compared to their separate usage, the co-treatment of exogenous GSH and Ca strengthened the GSH pool by increasing the activities of enzymes involved in GSH metabolism