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In isolated rat aorta preparations, the peptide produced concentration-dependent vasodilation that was endothelium-dependent and abolished by L-NAME, and co-immunoprecipitation work traced the response to phosphorylation of Src, caveolin-1, and endothelial nitric oxide synthase, with reduced binding between caveolin-1 and eNOS [1]

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The vial format supports precise dose-response studies in cell-culture and animal models of NNMT inhibition and adipose-tissue metabolic regulation

Cold peptide solution causes more discomfort at the injection site and can lead to increased local reactions