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It is built on a 37-residue modified human amylin / pramlintide-style backbone with three rationally designed substitutions (N14E and V17R to stabilise the central alpha-helix through a salt bridge, P37Y to enhance calcitonin-receptor potency) and N-terminal acylation with a C20 eicosanedioic fatty diacid attached via a gamma-glutamic acid linker
It is naturally derived from Palm oil
The next step is maintenance dosing, which well cover next
In another human study, Epitalon was applied to PHA-stimulated lymphocytes from adult donors aged 25 to 88 years
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