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As for the DUAL-1 study, the primary endpoint was to prove non-inferiority of the combination compared to glargine and superiority compared to lixisenatide
it is only available within authorised clinical trials and has not been approved by the MHRA or EMA
A 2020 overview of clinical trials found that intravenous vitamin C, melatonin, and glutamine each showed promise for specific side effects in certain cancer types, but results are variable, and larger trials are needed before routine use can be recommended
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