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This association further underscores the significant impact of obesity on patient outcomes in neurosurgical practice and emphasizes the need for careful consideration of surgical approaches in this patient population

GLP-1RAs are a novel class of glucose-lowering agents that mimic the physiological actions of endogenous GLP-1 by enhancing insulin secretion, reducing glucagon release, and acting on the brain to inhibit gastrointestinal motility, thereby slowing nutrient absorption

Rather than injecting large doses infrequently (most of which you will flush out within an hour), its much better to inject smaller, daily doses

Strength training plays a particularly powerful role