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10.1016/j.tips.2020.01.009 63 ShiH.HalvorsenY

The following recommendations support optimal outcomes: Prescribing decisions should be individualised, weighing the substantial benefits of improved glycaemic control and weight reduction against any theoretical skeletal concerns

This entire process takes about 15 seconds

The body compensates by increasing glucose oxidation and, more problematically, by increasing amino acid catabolism, which means breaking down muscle protein for energy