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These findings suggest caution in short-term use of these drugs without a more comprehensive approach to weight management. In an associated editorial, Qi Sun, associate professor of medicine at Brigham and Womens Hospital and Harvard Medical School, highlighted that obesity is not a disease that can be easily treated and managed and that the BMJ study findings cast doubt on the notion that GLP-1 receptor agonists are a perfect cure

Each is reconstituted separately with bacteriostatic water

The end result is a single molecule that can be injected once weekly and produces robust activation of both incretin pathways

10.1074/jbc.M310991200