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Jan 2025;99(1):153-209
Most users start noticing skin brightening within 4 to 12 weeks, depending on the dosage, skin type, and consistency
4.3 Glutamine Glutamine (Gln) is mainly converted through GLS/glutamate dehydrogenase (GLUD)-related reactions to generate -KG, which enters the TCA cycle and provides anaplerotic substrates for oxidative metabolism, while also influencing polarization-related epigenetic regulatory processes through metabolic ratios such as -KG/succinate (58)
Nature 457:849853
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