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Malabsorption (insufficient absorption of vitamin B12 in the intestine) due to insufficient production of intrinsic factor (a protein produced in the lining of the stomach that is needed to absorb vitamin B12), disorders in the end section of the ileum (part of the small intestine), such as sprue, fish tapeworm infestation or blind loop syndrome (change in the course of the intestine after gastric surgery)
Who may need a different path Beyond the formal contraindications, caution applies to people with a history of pancreatitis, severe gastrointestinal disease, or certain kidney conditions
Neither the European Food Safety Authority (EFSA) nor the GB Nutrition and Health Claims Register has approved any health claims for berberine related to weight management, reflecting the current insufficiency of evidence
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