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By entrapping bioactive compounds in nanocarriers (liposomes, lipid nanoparticles, nanoemulsions, biopolymer nanoparticles, etc.), researchers have observed protection against environmental stressors such as light, heat, oxygen, pH extremes, and moisture

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These hallmark lesions appear years, if not decades, before symptom onset and are associated with synaptic dysfunction, progressive neuronal loss, and widespread cortical and hippocampal atrophy

The specific dosages studied in many of these animal models are very high when extrapolated to human equivalent doses