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The most plausible explanations involve tissue-specific GIP receptor effects blocking GIP in certain brain reward pathways may reduce food motivation, while activating GIP in adipose and other peripheral tissues may improve insulin sensitivity

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Mazloomi SM, Samadi M, Davarpanah H, Babajafari S, Clark CCT, Ghaemfar Z, Rezaiyan M, Mosallanezhad A, Shafiee M, Rostami H (2022) The effect of Spirulina sauce, as a functional food, on cardiometabolic risk factors, oxidative stress biomarkers, glycemic profile, and liver enzymes in nonalcoholic fatty liver disease patients: a randomized double-blinded clinical trial

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