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We detected several other LOX-metabolites (4-, 14-, and 17-HDHA) in plasma and mammary fat pads of rats gavaged with DHA at 1.5 mL/Kg b.w
Supporting the Bodys Natural Detoxification The liver is the primary site of glutathione activity
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However, an uncontrolled increase in their concentrations leads to a chain of unwanted radical reactions that target the main biomolecules (DNA, RNA, lipids, and proteins) and alters key processes such as nucleic acid oxidation, lipid peroxidation, thereby contributing to the loss of cellular architecture, to impaired cell signalling and, ultimately, to cell death [25, 46]
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