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GGT reflects bile duct function and oxidative stress
Retatrutide, a new peptide in clinical trials, shows strong weight-loss potential by targeting three hormone pathways, but raises concerns about side effects, and mental health impact
For patients with significant obesity and weight-related complications who cannot tolerate pharmacological options, bariatric surgery may be considered according to NICE criteria (typically BMI 40 kg/m, or 35 kg/m with comorbidities, with lower thresholds for people with recent-onset type 2 diabetes)
We also mentioned less common causes like tears in the esophagus and a specific type of lesion
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