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The picture illustrated was much more complex, because in several experimental systems, cell viability was not affected when GSH depletion was obtained chemically by inhibition of its synthesis
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Computational protein modeling studies further suggested that baicalin possesses a high predicted affinity for HSP70 and HSP27, indicating a possible direct interaction with these proteins and a potential role in regulating heat stress-related protective mechanisms (Kumari et al., 2026)
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