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The human dopamine transporter (hDAT) contains a high-affinity, extracellular, and allosteric Zn 2+ (zinc ion) binding site which, upon zinc binding, inhibits dopamine reuptake, inhibits amphetamine-induced hDAT internalization, and amplifies amphetamine-induced dopamine efflux
However, less than 1.000 MDS were available for those meta-analyses, and subgroup stratification yielded inconclusive results likely because of the small case-control cohorts in each ethnic group (Copped et al., 2013c
While this may help with weight loss, it also increases the risk of eating too little or missing out on important nutrients
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