Common experiences at 1.0 mg: Consistent weekly weight loss of 0.5 to 1.5 pounds Significant reduction in hunger between meals Possible intermittent nausea, usually manageable and less intense than at 0.5 mg Increased fullness after smaller portions Some people develop mild acid reflux at this dose If the B12 component of your compounded formulation is going to show its value, this is when it starts mattering
McIntyre N, Holdsworth CD, Turner DS: Intestinal factors in the control of insulin secretion
reports personal consulting fees from Astra Zeneca, Fractyl, Hanmi Pharmaceutical, MBX Biosciences, Recordati, Poxel, Eiger Pharmaceuticals, and Xeris and grants from Chan-Zuckerberg Initiative, Dexcom and Helmsley Trust, outside the submitted work
This can be beneficial for people with NAFLD, as excess fat in the liver can lead to liver inflammation and damage over time