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First, assess for melanoma When a patient with a suspicious skin lesion presents in general practice the first step is to assess the risk of a melanoma being present
The melanoma precursor most probably originates from a stem/progenitor cell that has undergone cytogenetic alterations and consequently expresses dysregulated developmental signalling pathways and transcription factors, ultimately acquiring a malignant phenotype
European Journal of Endocrinology , 139 (5), 552561
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