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There was significant correlation between the decreasing ejection fraction percentage with HMGB1 as well as a significant positive correlation with the immune biomarker, TLR4 which has HMGB1 as one of its corresponding ligands highlighting their importance as biomarkers of diabetes-induced cardiomyopathy

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Binding of bile acids by glutathione S-transferases from rat liver [PMID: 3783048] Laboratory literature summary: Binding of bile acids by glutathione S-transferases from rat liver