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The levels of Keap1 in groups DM and DME were higher than those in group C and D (p 0.05)

How to store the Ozempic pen 1 Prior to first use Until expiration date Refrigerated 36 F to 46 F (2 C to 8 C) After first use 56 days Room Temperature 59 F to 86 F (15 C to 30 C) Refrigerated 36 F to 46 F (2 C to 8 C) How to dispense Ozempic 1 Ozempic 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) NDC: 0169-4181-13 Days supply: Sample/initial (42 days) 1-month supply (28 days) Intent of prescription: Sample or initial prescription for new starts 1-month prescription for maintenance on 0.5 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg after at least 4 weeks on 0.5 mg Strength: 2 mg per 3 mL (0.68 mg/mL) Dosage form: Solution SIG: Sample or initial Rx: Inject 0.25 mg SUBQ once weekly for 4 weeks, then 0.5 mg SUBQ once weekly for 2 weeks Maintenance Rx: Inject 0.5 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 6 included Number of boxes: 1 box Ozempic 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) 0.25 mg or 0.5 mg dose (2 mg/3 mL subcutaneous pen injector) NDC: 0169-4181-13 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 0.5 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg after at least 4 weeks on 0.5 mg Strength: 2 mg per 3 mL (0.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 0.5 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 18 included Number of boxes: 3 boxes Ozempic 1 mg dose (4 mg/3 mL subcutaneous pen injector) 1 mg dose (4 mg/3 mL subcutaneous pen injector) NDC: 0169-4130-13 Days supply: 1-month supply (28 days) Intent of prescription: 1-month prescription for maintenance on 1 mg Strength: 4 mg per 3 mL (1.34 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 1 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 4 included Number of boxes: 1 box Ozempic 1 mg dose (4 mg/3 mL subcutaneous pen injector) 1 mg dose (4 mg/3 mL subcutaneous pen injector) NDC: 0169-4130-13 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 1 mg For patients with T2D and CKD, increase to the recommended maintenance dose of 1 mg Strength: 4 mg per 3 mL (1.34 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 1 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 12 included Number of boxes: 3 boxes Ozempic 2 mg dose (8 mg/3 mL subcutaneous pen injector) 2 mg dose (8 mg/3 mL subcutaneous pen injector) NDC: 0169-4772-12 Days supply: 1-month supply (28 days) Intent of prescription: 1-month prescription for maintenance on 2 mg Strength: 8 mg per 3 mL (2.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 2 mg SUBQ once weekly for 4 weeks Dispense quantity: 3 mL Dispense quantity unit of measure: mL ONLY Needles: 4 included Number of boxes: 1 box Ozempic 2 mg dose (8 mg/3 mL subcutaneous pen injector) 2 mg dose (8 mg/3 mL subcutaneous pen injector) NDC: 0169-4772-12 Days supply: 3-month supply (84 days) Intent of prescription: 3-month prescription for maintenance on 2 mg Strength: 8 mg per 3 mL (2.68 mg/mL) Dosage form: Solution SIG: Maintenance Rx: Inject 2 mg SUBQ once weekly for 12 weeks Dispense quantity: 9 mL Dispense quantity unit of measure: mL ONLY Needles: 12 included Number of boxes: 3 boxes More ways to help your patients with T2D Check your patients' coverage and view savings offer Learn how to properly administer Ozempic pen pen CKD=chronic kidney disease

Ipamorelin mimics the ghrelin and binds to the ghrelin receptor in the pituitary gland in the brain

They support red blood cell production, DNA synthesis, and normal nerve function when deficiency is present