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Most antipsychotics contribute to weight gain, with the highest risk associated with olanzapine and clozapine (Dayabandara M et al, Neuropsych Disease Treatment 2017;13:22312241
Peptides are often degraded faster than steroids, so dosing frequency can increase
Because IGFBP-3 also carries IGF-1, when IGF-1 is administered on its own, the carrier IGFBP-3 saturates with IGF-1 displacing IGF-2 and thus augments its free circulating concentration
Dark patches, brown spots, and discoloration can make the skin appear dull, tired, and uneven, often affecting self-confidence and overall appearance
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