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In UK clinical settings, the recognised standard diluent for injectable medicines is Water for Injections BP (single-use, preservative-free), and the choice of diluent must always follow the licensed product's Summary of Product Characteristics (SmPC)

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When to stop Stop the protocol and contact your provider if you experience persistent redness or swelling at injection sites beyond 72 hours, fever, or any systemic symptom that does not correlate with the expected mild post-injection reaction

These side effects were usually mild or moderate, often improved with time, and only a small number of participants stopped treatment because of them