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TMAO can change the bile acid spectrum to accelerate the formation of aortic lesions in ApoE / mice, and further activate the nuclear receptors farnesoid-X-receptor (FXR) and small heterodimer partner (SHP), to reduce the expression of cholesterol 7-hydroxylase (Cyp7a1) to inhibit bile acid synthesis, thus accelerating the formation of atherosclerosis (82)

Glutathione (GSH) tham gia tng hp leukotriene v l ng yu t ca enzyme glutathione peroxidase

While we still lack safety trial data for DSIP, early studies suggest that even at low doses DSIP can normalize sleep and exert strong neuroprotective effects

Pollak, M