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The extracellular domain of the EpsteinBarr virus BZLF2 protein binds the HLA-DR beta chain and inhibits antigen presentation
Browse our Semaglutide diet guide for food lists and meal planning tips that help you get your nutrition under control
Lactococcus lactis , an attractive cell factory for the expression of functional membrane proteins
Conditions include alcoholic liver disease, viral hepatitis, cirrhosis, and primary or metastatic liver cancer Renal dysfunction : Impaired kidney function reduces B12 elimination, causing accumulation even with normal intake Haematological conditions : Myeloproliferative neoplasms, chronic myeloid leukaemia, polycythaemia vera, and hypereosinophilic syndrome increase transcobalamin production, elevating total serum B12 Laboratory interference : Macro-B12 (immunoglobulin-bound B12) and assay interference can cause spuriously elevated results without true excess In clinical practice, unexplained hypercobalaminaemia should prompt investigation for underlying disease, particularly in patients without obvious supplementation history
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