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Alterations in the concentration of iron have been observed in amyotrophic lateral sclerosis, spastic paraplegia, and multiple sclerosis which strengthens the knowledge that the accumulation of iron is a secondary factor that is related to neurodegenerative diseases
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FIGURE 1 4 Biological measurement indicators A variety of biological parameters are employed to assess OS in ALD (Wu and Cederbaum, 2009)
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