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8 As Glutathione plays a central role in antioxidant defense and cellular resilience, when levels drop, we can become more vulnerable to oxidative stress, which is linked to inflammation, fatigue and slower recovery

The malfunction of methylation in the developing brain due to inherited mutations, compounded by epigenetic stresses, underlies the pathological process of a variety of neurodevelopmental and/or psychiatric disorders, including diseases that manifest at different stages of life, such as MDD and SZ

Chasman, D

This is why patients with neurological involvement are often maintained on a more frequent schedule (every 2 months rather than every 3 months)