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In the STEP 1 trial, participants using semaglutide 2.4 mg weekly (marketed as Wegovy) lost an average of 14.9% of their body weight over 68 weeks
The primary reason is still sustainable weight change under medical supervision
The through line of history is that people will try to sell anything with all sorts of fantastical claims, Joshua Sharfstein, a health-policy professor at Johns Hopkins and a former principal deputy commissioner of the F.D.A., told me
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