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Additionally, IGF 1 LR3 has demonstrated protective effects against age-related cognitive decline, preserving memory and reducing the risk of neurodegenerative conditions
Front Immunol (2019) 10:1743
BBB restrictions: The BBB serves as a barrier that hampers the passage of specific phytochemicals into the brain, posing a challenge for these compounds to exert their neuroprotective effects directly at the injury site
Hypoxia and inflammation activate p53 via phosphorylation
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