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while excessively high levels of ROS causing lipid, protein and DNA cell damage are known as oxidative stress (Schieber and Chandel, 2014)
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This has triggered speculation that the peptide might have a larger and more universal role in influencing physiology
Chemical structure of polymyxin B and colistin The core structure of PMB and CST comprises a cyclic heptapeptide linked to a tripeptide side chain, acylated at the N-terminus by a fatty acid ( Fig
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