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Among the series of analogues, including GLP-1 (137), GLP-1 (637), GLP-1 (737), GLP-1 (837), etc., only those which start with His 7 retain their insulinotropic activity
i , Representative trace showing that 50 M GLP-1MK-801 acute bath application induces a depolarization of POMC neurons in ARC ( n = 6 of 17 neurons)
Ongoing research into mitigating these side effects and the development of more cost-effective alternatives are crucial for overcoming these restraints
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