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World Anti Doping Agency
The 28-day refrigerator stability window is the practical limit, not the volume in the vial
Deficiency can develop gradually and may cause symptoms ranging from fatigue and weakness to neurological problems
Seiwerth and colleagues (Inflammopharmacology, 1999) documented effects on angiogenic growth factor pathway signalling, and subsequent work has expanded characterisation to include VEGF receptor 2 upregulation, endothelial cell migration in capillary-formation assays, and improved healing in ischemia-reperfusion preparations
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