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Wegovy received FDA approval in 2021 for weight loss in adults and teens with obesity or overweight, and in 2024 gained additional approval to help reduce cardiovascular risk in adults with obesity or overweight and heart disease

Many patients begin to notice appetite reduction and early weight loss within the first 68 weeks, although the rate of progress varies

MUC1 has been demonstrated to prevent ferroptosis in AT2 cells by promoting Nrf2 nuclear translocation, increasing GSK3 phosphorylation, decreasing KEAP1 expression, and raising GPX4 levels (44)