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Interestingly, this side effect was more common in individuals with darker baseline skin and in those who took many doses
IF staining demonstrated reduced expression of GPX4 and Nrf2 in the OVX group relative to the Sham group, with restoration observed upon 4-OI treatment
Notably, exposure to nicotine-free e-vapor induces significant metabolic alterations and liver injury in dams and progeny, whereas nicotine-containing e-vapor promotes hepatic steatosis in adult offspring [135]
A small subset of people experience increased risk of alcohol or other substance use disorders post-operatively, particularly following gastric bypass procedures.309 Population data suggest new-onset substance use disorder occurs in a small minority
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