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For research mainly targeting the gut tract, oral use may be considered, though uptake may be lower and higher doses may be necessary
In MBA-15.4 murine bone marrow stromal osteoblast cells GCs cause rapid activation of MAPK-1 and dephosphorylation of extracellular signal-regulated kinase (ERK) as well as impaired proliferation [26]
MOTS-c promotes NRF2 activation, upregulating genes for glutathione synthesis, superoxide dismutase, and catalase [3]
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