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Going back to SCFAs, butyrate, propionate, and acetate were observed to possibly induce the expression of forkhead box protein 3 (Foxp3) to trigger the development of Treg while inhibiting CD4 + T cells ( 3.3 Gutendocrinebone axis: intervention of hormones and other endocrine substances 3.3.1 Endocrine hormones related to both the gut and the bone The endocrine pathway is another indirect form of the gutbone axis, in which the involvement of different types of hormones ranks as the most important aspect

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