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If you're on a 1ml weekly protocol and seeing no measurable change after six weeks, the problem is almost never 'too low a dose.' It's either formulation quality (underdosed methionine or choline), dietary interference (you're in maintenance calories, not deficit), or liver saturation (you're already consuming high dietary methionine and adding more doesn't shift the pathway further)
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Ciproxifan improves cholinergic transmission, attenuates neuroinflammation and oxidative stress but does not reduce amyloid level in transgenic mice
Gastrointestinal Disorders: People with gastrointestinal conditions, such as Crohn's disease, celiac disease, or atrophic gastritis, which might hinder the absorption of vitamin B12 from the diet, may be administered it
