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Manifestations of hepatic oxidative damage include dysregulation of lipid metabolism (leading to steatosis), hepatocyte degeneration and death, and activated immune response (leading to inflammation and fibrosis/cirrhosis)
She pointed to the shrinking availability of extended sizes, fewer jobs for plus-size models, and the way all of our big girls are not-so-big anymore as evidence that the body positivity landscape has shifted dramatically
This level of weight reduction rivals surgical outcomes and represents a paradigm shift in non-invasive obesity treatment
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