AK-K: Methodology, Writing original draft
Importantly, accumulating evidence indicates that exercise can overcome both intrinsic and extrinsic barriers to central nervous system (CNS) regeneration in adults, including by stimulating neurogenesis, remyelination, glial phenotypic switching, neuroimmune balance, angiogenesis, bloodbrain barrier (BBB) repair, and mitochondrial metabolism [2,3,4,5,6]
For the RSABE analysis, only participants with a value for an endpoint at all four steady-state periods contributed to the statistical analysis of the respective endpoint
In a study of patients undergoing cardiac valve replacement surgery with cardiopulmonary bypass (CPB), patients were randomly assigned to the dexmedetomidine (Dex) group or the placebo group