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Ro does not currently offer non-injectable GLP-1 options like oral tablets or lozenges, which some patients may prefer
Not for human or animal use
These direct effects are further supported by human studies demonstrating the wide expression of GLP-1 receptors in the proximal tubules, juxtaglomerular cells, hilar and intralobular arteries, and preglomerular vascular smooth muscle cells [49]
Additionally, the presence of CKD, whether pre-existing or newly developed post-transplant, compounds the challenges faced by these patients, creating a double hit scenario that further complicates their management
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