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Psoriasis patients with diabetes type 2 are at high risk of developing liver fibrosis during methotrexate treatment
The benefits are genuine, but they flow through the vasculature, the nervous system, and secondary mediators more than through the organs working cells, a distinction that matters when designing drugs meant to target these tissues
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As a thyroid hormone receptor agonist, resmetirom improves hepatic steatosis, inflammation, and fibrosis while providing lipid and cardiovascular benefits
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