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K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts
4.2.2 Clinical studies in people with PD About a dozen clinical studies on microbiome-based supplementation have been published to date and have been included in a recent comprehensive review (131) and a systematic review with meta-analysis (134)
The effects of fatty acids usage depend on the type and duration of their use [140]
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