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Furthermore, the use of ferroptosis inhibitors like DFO and Fer-1 has been found to enhance motor function recovery following SCI (Li and Jia, 2023)
Tendons and ligaments: Have low vascularity (limited blood flow) Depend heavily on collagen alignment and remodeling Heal slowly and often incompletely Are prone to scar tissue and reinjury Traditional treatmentsrest, physiotherapy, NSAIDs, corticosteroid injectionscan reduce pain but often do not improve tissue quality
However, the expression of GPx1 has been reported to be down-regulated in thyroid cancer [44], colorectal cancer [45, 46], and gastric cancer [47], whereas GPx1 has been demonstrated to play an oncogenic role in kidney cancer [48], pancreatic cancer [49], and laryngeal squamous cell carcinoma [50]
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