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The weighted Unifrac based principal co-ordinates (PCoA) analysis was conducted to reflect differences in community structure of gut microbiota in each group, ANOSIM analysis was used to evaluate the statistical differences among groups

PIONEER 1: Randomized clinical trial of the efficacy and safety of oral GLP1 monotherapy in comparison with placebo in patients with type 2 diabetes

J.PinkhasovaV.SyedM.KaoH.-Y.JozwickaA.ZhaoN.et al

Figure 2 3.4 Correlations between S-5-HT and fatigue levels There was a negative correlation between S-5-HT and fatigue scores, such that increased serotonin levels were associated with reduced fatigue