Instead, discuss any changes in sexual function with your healthcare provider, who can assess contributing factors, adjust treatment if needed, or provide referrals to appropriate specialists for comprehensive management
And in blood vessels that are already less flexible or have cholesterol plaques, reintroducing estrogen in the form of hormone replacement therapy can increase the force and speed of blood flow with each heartbeat, sometimes causing a plaque in a vessel to break off and raising the risk of serious problems like heart attack, stroke, or blood clots, says Chervenak
Understanding this pharmacological foundation helps contextualize why some individuals may experience persistent hunger despite treatment, as the biological response to GLP-1 receptor agonism involves complex interactions between peripheral and central nervous system pathways
For more background on that comparison, our article on whether berberine and GLP-1 are the same explains the difference in more detail